Too depressed to get off the couch?
![gene_synth[1].jpg](http://trouble.philadelphiaweekly.com/archives/gene_synth%5B1%5D.jpg)
Drooling onto the pillow in your bed in your sleep instead of going to work? Now that saliva can be put to use. Reuters spills the beans about a new spit test for bipolar disorder:
The $399 kit uses a saliva sample to test for one of the likely dozens of genes associated with bipolar disorder, GRK3; the results and a report are mailed to your physician. The company's website states that if you have the gene, you are two to three times more likely to have the disorder, depending on the particular gene variation found.But the test cannot give a definitive diagnosis or predict future risk of developing the disorder, and a negative test does not rule out bipolar disorder. As well, the test results are only valid for Caucasians with Northern European ancestry who have at least one relative with bipolar disorder, and who are exhibiting symptoms of the disease themselves.
So, as my Jewish relatives would say: What could be wrong? A LOT.
What it boils down to is that the information provided by the existing tests don't add or subtract anything of value, [Harvard Medical Letter editor Michael C.] Miller said. They just provide a result that may confuse more than it clarifies."Sometimes a little knowledge is a bad thing," he said, "especially if you don't know how to interpret it."
There is also the issue of privacy. On Thursday, Congress passed a bill that protects individuals against discrimination based on genetics. But putting your genes -- especially as related to psychiatric health -- on record, could still come back to haunt you later, warned Miller, adding that mental health is still poorly understood, which allows a person's psychiatric history to be manipulated.


Comments
What will they think up next?
Posted by: Mitchell Gobrick | May 3, 2008 09:47 PM
To think that it took years to get to a diagnosis for me! But if we had this test, all I had to do was be a Northern European white who was clearly bipolar and this would have said I might be bipolar. How ridiculous.
Posted by: scott | May 3, 2008 11:35 PM
The prevalence of bipolar is usually estimated to be between 2-3 and at the high end is estimated to be six percent. So if you test positive for the genes in your saliva you have a 4-18 percent chance of being bipolar. Not sure how this helps. Seems like if anything a way for insurance companies to herd otherwise healthy people into a high risk group of people who may have mental problems.
Posted by: Donald | May 6, 2008 04:55 AM
liz: i came across this link of yours (blog?) and am very impresed by what I just read - it was a quick look see and I'd like to be able to communicate w/you (or others) more re the stigma or mental illness, etc.
Posted by: sharon regan | May 10, 2008 11:19 AM