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December 29, 2006

Business argot, then translation

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I read the following big-pharma stock market update without comprehending a word of it. In fact, as soon as I realized the subject matter was financial, I broke out into a cold sweat and my face started to melt.

Thank goodness Business Week digested it and then regurgitated it in a language even I can sort of understand.

(RTTNews) - Targacept (TRGT | charts | news | PowerRating) revealed Wednesday that AstraZeneca (AZN | charts | news | PowerRating) decides to continue development of AZD3480 in Alzheimer's disease and cognitive deficits in schizophrenia. The company stated that under this collaboration deal it would receive $20 million Payment from AstraZeneca. The company noted that this announcement follows the finalization by AstraZeneca of previously disclosed studies of AZD3480. Targacept climbed in early trading Wednesday, but lost momentum and saw little movement through mid-day. The stock has, however, climbed further in the last few minutes. The stock is higher by $2.25 at $9.69 on the year's heaviest volume and is trading at a new historic high. Previous to today's move, the stock had been range-bound since early November./ Copyright(c) 2006 RealTimeTraders.com, Inc. All Rights Reserved

Translation after the jump.

From Business Week:

Targacept to get $20 million milestone

Biotech drug developer Targacept Inc. said Wednesday that it will get a $20 million milestone payment from British drugmaker AstraZeneca PLC with the continued development of an Alzheimer's disease treatment.

Targacept shares rose $1.82, or 24.5 percent, to $9.26 in morning trading on the Nasdaq, after setting a new 52-week high of $9.75 earlier in the session. The stock's previous year high of $9 was set in April.

The agreement covers the development of drug candidate AZD3480 to treat Alzheimer's and cognitive deficits caused by schizophrenia. The milestone payment was triggered when AstraZeneca decided to continue developing the drug.

Targacept originally received an upfront payment of $10 million from AstraZeneca, and stands to receive up to $249 million in payment under the agreement, along with double-digit royalties.

The company also expects a total of about $26.4 million in development funding from AstraZeneca over four years.

American depositary shares of AstraZeneca rose 27 cents to $53.85 on the New York Stock Exchange.


Mental illness made me do it: Steal lingerie

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From IOL:

Taipei - A Taiwan man has been sentenced to eight months in jail for stealing women's lingerie, a newspaper reported on Friday. Chang Cheng-wei, 31, from Taichung City in central Taiwan, has stolen at least 109 pieces of lingerie over the past three years.

The report said a woman had been losing lingerie drying on the wash-line on her balcony for a long time. So she installed a security camera, which caught Chang in the act.

Chang claimed he suffered from mental illness which caused him to steal lingerie and pleaded for leniency, but the judge said that if Chang was ill, he should have seen a doctor. Since he had disturbed local residents' lives, he deserved to be put in jail. - Saoa-dpa

[Image from—where else?—Frederick's of Hollywood.]

The perils of tough love

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Thanks to Amara for sending me the below article about troubled kids from Reason Magazine . The whole notion of "tough love" is problematic; it leaves so much room for abuse. Really deliinquent kids are often sent to so-called boot camps where they're ostensibly taught discipline. The issue with such places is that for every kid who thrives in that environment, there are probably two or more who are traumatized. Kids die from abuse in such programs—abuse disguised as discipline. The problems have been serious enough for Jeb Bush, no soft touch, to shut down Florida's state-run youth boot camps and forbid like programs that still exist from employing physical and psychological punishment. But as this article makes clear, such prohibitions can only be enforced to a certain degree. Private programs are exempt.

The Trouble with Troubled Teen Programs: How the "boot camp" industry tortures and kills kids

[Photo by Rochie via Flickr.]

BBI: Reminder: Medicare Open Enrollment Date

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Open enrollment for some people ends this weekend, so keep the following in mind. [Thanks to A-List Promo for the image.]

From NAMI:

Who Needs to Contact Medicare Before Midnight December 31? The short answer is anyone who wants to switch their drug coverage for the coming year, or who did not enroll in 2006. In addition, Medicare beneficiaries who are happy with their prescription coverage also need to carefully check into changes in coverage for 2007 including:

Changes in premiums and cost sharing,
Adjustments to formularies (the list of covered drugs),
Movement of specific drugs to different cost sharing tiers, or
Imposition of new or different utilization management policies on specific medications (prior authorization, step therapy, quantity limits, etc.).

If a Medicare drug plan made any of these adjustments to their coverage policies for 2007, then they were required to notify all enrollees in writing by October 31 through an "Annual Notice of Change" or ANOC letter. In addition, Medicare has also been sending notices of changes in coverage in recent, especially for dual eligibles whose status as "Low Income Subsidy" is changing (see details below).

"Re-Deeming" of Certain Dual Eligibles Of particular concern to NAMI in the transition to the new plan year on January 1 are low-income Medicare beneficiaries who had dual eligible or "Low Income Subsidy" (LIS) status in 2006, who will not in 2007. These are individuals that prior to 2006 qualified for Medicaid in their state as a result high medical expenses and "spend-down" eligibility. Most of these dual eligibles were automatically enrolled in a Part D plan for 2006.

For 2007 however, many will not have dual eligible status because they never reached the Medicaid "spend-down" level in 2006. Others have experienced some other "change in status" that has prevented CMS from "deeming" them (making them automatically) eligible for LIS or dual status in 2007.

These individuals will need to send in a new application for the Medicare Part D "Low Income Subsidy" (LIS) in order to access affordable drug coverage for 2007 (in most cases, coverage with no monthly premium, no deductible, no gap in coverage and as little as $3 for a generic, and $5 for a brand name prescription). A number of Part D drug plan sponsors have already announced their intentions to provide a 90-day grace period in which higher cost sharing and deductibles will NOT be assessed against anyone losing "deemed" dual eligible or LIS status. Further, CMS is providing a special 90-day open enrollment period (through March 31, 2007) under which low-income beneficiaries losing automatic dual eligible for LIS can select a different drug plan if they wish.

Notices from CMS to these "deemed" individuals were sent in September (a letter printed on blue paper), with an LIS application and postage paid envelope. For more information on this important issue, click here and here.

More Web-Based Tools Available

In addition to the resources listed above, more web-based information about the Medicare prescription drug benefit is available through the following links. The new "My Health/My Medicare" Campaign designed to promote on-line personalized information.

Mental Health Part D

Map of Rx


December 28, 2006

I try to be open-minded...

I'm fascinated by this kind of thing. Sure, the lady could've been paid. She could've been faking. And yes, this guy looks and talks like Thomas Haden Church and should probably dry his hair when he gets out of the shower. But what if this works? I have such a terrible phobia of vomit, and it really causes me a lot of trouble. I don't think I could go through a similar treatment given the nature of that phobia, but boy, I'd love to have it resolved.

Slow Jews day

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Ha ha. I'm making fun of the fact that I'm jetlagged and sleep-deprived. Don't worry—I've got a million like that one.

Though you might be breathing easy because the holidays are over, don't let your guard down. We still have to survive New Year's Eve, which is arguably more depressing because you always think, "Maybe next year will be bettter," which then causes you to think about last year and why it didn't meet your expectations. Plus, you've eaten all kinds of crap over the holidays and have gained five pounds and you know your NYE resolution to lose weight will only make you glum.

Oh, sorry. Am I projecting?

Anyway, if you're still feeling like you're having a hard time, check out "Mental Illness: Coping With the Holidays" from Mental Health Ministries. Download it here.

[When I looked at the NAMI press release about the brochure, it mentioned Rohatsu, and I was all, "whahatsu?" It's a Japanese Buddhist holiday, hence this image from buddhamuseum.com.]

Glad tidings for 2007

This sentence from an Associated Press article by Frederic J. Frommer gives me hope for the new year:

After years of trying, advocates think they have a good chance of getting Congress to pass legislation next year that would require equal health insurance coverage for mental and physical illnesses, if their policies include both.

Yeah, baby! Apache jump on it!

Mental health bill to face House vote

Noose removal

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In the U.K., where there's a problem with suicidal prison inmates, guards will now be given knives, which they're expected to use to cut people down when they try to hang themselves. This solution came as a result of the discovery that 90 percent of inmates that attempt suicide do so by hanging. The knives aren't really knives; they're more like scythes designed to cut through rope and fabric. Sounds kind of like a fishing gaff or something. While I appreciate the effort to pay attention to this issue, maybe they should be asking why so many of their inmates are suicidal, and deal with that.

Prison issue knives to officers to cut suicide rate

[Don't use the knife in this photo if you're planning to cut a noose. It's good for newsprint, though.]

Cutie pie

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For last week's column, I wrote about CuteOverload.com, and the deliciousness therein.

THE TROUBLE WITH SPIKOL

Precious Matters

What happens when my two passions—bargains and adorableness—collide.

by Liz Spikol

There are certain words that make my heart beat faster. “Value,” for one. “Dollar,” for another. “99 c.”—arguably not a word—is especially beguiling.

This is not, as you might think, because I’m cheap—or poor. I’m doing okay. But it’s a question of values.

Why spend $3 on toilet paper if you can spend $1? Why buy a $28 candle when you can buy one for a dollar? Why buy $12 place mats at Pier 1 when you can find the same exact place mats for $1 each?

These aren’t rhetorical questions. I really want to know.

Until I’m persuaded otherwise, I’m sticking with Value City, where I recently purchased a cottony nightgown with yellow ducks on it. I say, “cottony” because I think it’s actually made of flammable plastic softened by boll weevils under the influence of too many pesticides. But it sure is cute. And it cost $3.

When I got it home I put the nightgown on over my clothes—that’s how excited I was to own it—and ran to the mirror, where I discovered one size does not really fit all. It was much too long, and it billowed ridiculously around my thin frame. (Yes, I’m saying thin frame. You want to argue?) The lace up the front was like a brittle shredded doily. The buttons were strangely slippery—maybe from the pesticides.

But the duckies! So incredibly cute. And if there’s any word I love as much as “value,” it’s “cute.”

My cute obsession is all encompassing and borderline self-destructive. I spend hours poring over photos of puppies, kittens and all other baby animals. That there’s now ample video footage online just makes it worse. How can I not click on a clip titled “The Tiniest Mew”? What am I, made of steel?

When I see cuteness, my insides melt. My blood pressure drops, and I get dizzy. I feel elated and unbearably moved. Tears form in my eyes, and I feel the world has been carefully designed to meet my needs. It’s everything I searched for in religion but never found.

Consequently, I cruise YouTube’s cute offerings like a sweaty-browed porn addict. I look for new videos because they stop “working” after about 10 views. I get ridiculously excited when I see there’s a new video of basset hound puppies—preferably with big, floppy ears they’ll trip over.

If the computer stalls while loading a video of kittens “discovering the big bed,” I get panicky and frustrated. When the little mewling and purring of the kittens on-screen gets too loud, I turn down the volume on my computer so no one knows what I’m doing. And I always keep another browser window open so I can toggle quickly between screens. Is this not a cry for help?

Thankfully, my job requires that I search for cuteness. I have a “cute fix” category on my website—which, I’ll remind you, is a blog about mental health. Every couple of days (not more often; that would seem desperate) I post a cute picture, ostensibly because people with mental health issues could use a little cheering up. In reality, the feature serves my addiction, making blog readers unwitting enablers.

The sine qua non of online cuteness is, of course, Cute Overload, the creation of the brilliant Meg Frost. On the site Frost employs her Rules of Cuteness to assess submissions, and she’s developed a cuteness dialect—including words like “baroo” and “anerable”—that other cute addicts employ in the comments section.

Not surprisingly, the comments aren’t the sophisticated political commentary you might find, say, on Daily Kos.

Here are a few examples I found in response to a photo of puppies inside a plastic bin of mint candy: “eeeeeeeeeeek puppehs!!!” And “Them’s some sleeeeepy lil stubbypuffs!” And, more sensibly, “That is so cute! Look at the little leg dangle! I bet their fur is so silky. I’d love to rub lil warm pupper body again my cheek.”

I’ve never felt so much kinship in my life. These are my people.

I’ve long wanted to be one of Cute Overload’s so-called cuteologists, but my submissions haven’t made the cut. I did place myself—defiantly, I’d say—on the Cuteologist Map, which features cute hunters from everywhere from Finland to Australia. And a video of my sugar gliders made it onto Cutecast, which is Cute Overload’s new video component. But it’s not the same. Until I get onto the home page, I won’t be satisfied.

But everyone hits rock bottom. Walking out of the gym the other day, a little girl passed me on the stairs. Generally, I don’t respond as acutely to human cuteness, but she was pretty charming.

I’d seen her marching around the gym in imitation of the adults, and it made me feel tender. I looked at her tiny nose and pink cheeks, and smiled at her in a goofy way.

She turned to watch me go, and then called after me, “I like your Hello Kitty backpack!”

Suffice to say, I’m getting a new gym bag. Is a Pikachu backpack too silly? Because he’s awfully cute, and I know where I could get one for cheap …

CO’s Rules of 
Cuteness (a Sample)

>> More than one species of baby flopping around is cute.

>> A thing, accompanied by a smaller version of that thing, is always cute.

>> Piles of a cute thing jack up a cuteness rating exponentially.

>> Fuzz + floppy limbs = cute.

>> A cute animal + food = even cuter.

[This photo is my latest submission to CO. I think it's a winner.]

December 26, 2006

Depression Confession: Jessica Simpson

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Jessica Simpson is down in the dumps. She fled the stage while singing "9 to 5," a truly awful song, at the Kennedy Center awards ceremony, and Nick Lachey has moved on to someone nicer and cuter, while she's left with her now-pretty sister Ashlee. (At least before Ashlee's nose job, she could console herself by saying she's the hot one in the family. No more.)

What's the solution? According to Fametastic.com, to go to Colorado instead of Hawaii. Isn't that backwards? Hmm. At any rate, if you care about all this, feel free to go to the link below. Personally, I'm falling asleep just thinking about it.

Jessica Simpson scales down Christmas holiday due to depression

[This photo is from Jess' happier days, when she felt both patriotic and lewd simultaneously.]

New blog!

My favorite theater company now has a blog. The company is truly remarkable, with such a great sense of humor. Even if you don't enjoy theater as a medium (as I don't) these guys will make you laugh.


Le Pigblog

Ou est moi?

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In case you wondered, I'm still in L.A. Today I'm hoping to see the world-famous Tar Pits and go to an outdoor farmer's market. I wish this felt more like a real vacation, but I don't feel truly unencumbered unless I'm by myself. I suppose it's because socializing can be a bit of an effort. I'm one of those people who needs approval and wants to be liked, which means I try not to have any "off" moments. I also am aware that people know about my mental health problems, and I want to be a good poster child—proving, through my behavior, that it's possible to be functional and friendly and happy and personable even with a serious mental illness. Even though I still struggle with mood changes and med maintenance, I consider myself in recovery, at least compared to how I used to be. So I feel like wearing a sign around my neck: "Recovery is possible!" What a dork.

I'm hoping to be able to post one more item later, en route, and one more tonight. If you're on the East Coast, my schedule might be a little annoying. And if I can't get a wireless signal later, I guess I won't be able to post much. Oh, and here's the deal for tomorrow: I'll be on a plane for most of the day, so the posts will be scarce. But Thursday I'm back full-throttle.

I hope you've all had a wonderful or at least bearable few days during this annoyiing Christmas season. Here's a link (thanks, HS!) to another good NYT article about troubled children to keep you busy.

[When I went to take a photo for this post, something weird happened. Dude, I'm feeling so fragmented.]

Zyprexa

This is how I can tell my vacation is coming to an end: yet more revelations about Zyprexa, Eli Lilly and assorted bad people affiliated with both. For the latest, go to Philip Dawdy's Furious Seasons. He'll give you the lowdown.

December 25, 2006

The kind of job ad you should see more of

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Not the above sign, but this consumer-oriented help wanted ad, sent in by advocate Fran Hazam:

In the near future, the Community Support Programs Branch of the SAMHSA Center for Mental Health Services will be posting a job announcement for up to two Public Health Advisor position(s). Among other candidates, we would very much like to consider mental health consumers for these positions.

A special hiring authority, called Schedule A, allows the Federal government to hire people with psychiatric disabilities on a non-competitive basis. Although the position will be open for competition, the Schedule A provisions make it easier for us to consider qualified consumers for the position.

To help prepare consumers to apply for the upcoming position, we are providing the following information about how to apply under the Schedule A authority. Please save this notice so that you can refer readily to it when the announcement is released.

We look forward to announcing the positions not long after the beginning of the New Year, and to receiving a lot of great applications (through our human resources coordinator) in response.

Submitting an application

You will have to submit your resume through the on-line system at
www.usajobs.opm.gov. To prepare to apply, you may want to create an
account on this website now. Doing so will allow you to receive
automated job alerts and to post your resume online so that you have it
ready to submit easily once the announcement is released.

During the application process, be sure to indicate that you ARE
eligible for "noncompetitive appointment," appointment under "Schedule
A," "excepted service appointment," or appointment under
"5CFR213.3120(u)" whenever asked. This will ensure that we can use the
simplified procedures for hiring you.

Preparing your application

Be sure to write "Eligible for excepted service appointment under 5 CFR
213.3102(u)" on the resume that you submit.

You must meet all required qualifications for the position in order to
be hired. Applications are pre-screened by personnel officers
unfamiliar with variations in terminology used by the field. They must
be able to tell from your application that you meet the minimal required
qualifications in order to pass your name on to us for possible hiring.
Therefore, in preparing your application, be careful to use the same
words used in the vacancy announcement to describe your qualifications.
For example, if the vacancy announcement asks about your experience in
working with people with mental illnesses, be sure to use the phrase
"people with mental illnesses" in your response, rather than just
discussing, for example, your work with "children with serious emotional
disturbances"-the personnel officer might not realize that the latter
counts toward the qualification.

Providing "proof of disability" documentation and "certification of job
readiness"

Proof of the disability and certification of job readiness are required
for excepted service appointments of persons with psychiatric
disabilities. The following is a list of some examples of documents
that you can submit as proof of psychiatric disability:

- Statements or letters on a licensed physician's/medical
professional's
letterhead stationary.
- Statements, records or letters from a Federal Government agency that
issues or provides disability benefits (e.g., the Social Security
Administration).
- Statements, records or letters from a State Vocational Rehabilitation
Agency counselor.
- Certification from a licensed private Vocational Rehabilitation or
other
Counselor that issues or provides disability benefits.
- Certification, statements, records or letters from a State agency, or
agency of the District of Columbia or a U.S. territory that issues or
provides disability benefits.

Certification of job readiness is a determination that applicants with
disabilities are likely to succeed in the performance of the duties of
the position he or she is seeking. The same entities who may provide
proof of disability may also certify an individual's job readiness.

For more information about Schedule A and other "excepted service" or
"non-competitive" appointments

Much of the information presented here is paraphrased from information
presented on two sections of the Federal Office of Personnel Management
website. You can go directly to these sections through the following
links:

http://www.opm.gov/Strategic_Management_of_Human_Capital/fhfrc/FLX05020.
asp#itemA1

http://www.opm.gov/disability/hrpro_3-02.asp

If you don't want to go through this process, you can still apply like anybody else. However, we will not be able to use the special hiring authority that would make it easier for us to hire you.


December 23, 2006

"Bring the hat"

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Here I am in L.A., visiting Vince's family, and I've just learned a very important expression—so important I'm breaking my three-day vow of silence to bring you this:

Bring. The. Hat.

What does this credo mean? Well, let's let Joey Bertolini, 15, explain it since it's his coinage:

"So basically 'bring the hat' means to do the good thing or do the right thing, or like if you're gonna do something then just kick ass while you're doing it. So, for example [slurps grape juice], it could be used in place of 'good luck,' 'break a leg' or 'you rock, man.' Let's say I was moving the furniture in my friend's house. He would say to me, 'All right, we gotta move this furniture, but we gotta bring the hat while we're doing it.' Or for example if I was running a 10K, before the gun went off, my friends would tell me to bring the hat."

To clarify the past tense, says Joey:

"Never say, 'brung the hat.' It's an insult. You have to say, 'I just brought the hat.' You can also say, 'I just brought the hat all over BLANK.' For example, 'I just brought the hat all over that chemistry test.'

And finally: "Bring the hat has, to many, become more of a philosophy to base their life around than just a simple phrase. So always remember to bring the hat. In everything you do."

December 22, 2006

Signing off

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Hey everyone, I'm leaving this online earth and actually going outside in the air. I'll be offline until Tuesday afternoon and of course I'm afraid everyone will forget about me and not come back. But please come back! I'll miss you.

Here's a photo of me saying goodbye. Have a great holiday, and please please please take care of yourselves. My holiday-wellness list is here, in case you missed it the first time. I won't get all sentimental right now because New Year's will be the big thank you, but you've made my year so beautiful. Just FYI.

Oh, I almost forgot: One more Funday headline. Get this: Study of hallucinogen shows promise in treating mental illness. Stoner friends, high-five!

Funday: Think you're paranoid? Maybe you're a private eye!

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It's possible, says a new book, that Sir Arthur Conan Doyle was .... schizophrenic! Who doesn't love some good ol' literary and ahistorical speculation? (Was Abe Lincoln gay? Sure seems like it now.)

New book detects schizophrenia in Sherlock Holmes' creator

Funday: Headline of the day

Woman's bipolar disorder creates chance to serve others

Funday, for real

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Sorry for the sad posts! I'm going to L.A. in a couple hours, and then I won't be heard from again until Tuesday. You'll have to amuse yourselves in some other way, I guess. Sigh. But look what a positive story this is. First sentence:

"The Mental Health Center of North Alabama is helping adults diagnosed with mental illness to experience a taste of freedom."

Freedom! Yay!

Mental Health Center provides housing

Funday: ECT study shocks. Ha ha.

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As everyone who reads this blog knows, I had ECT in 1996. It helped me for about a month. I was back in the hospital exactly one year later, as depressed as ever. And then one year after that. Not only was the ECT ineffective, it was incredibly damaging to my cognitive functioning and memory. But sometimes it's hard to be sure of yourself when everyone "credible"—scientists, ECT docs, researchers—are telling you that your reality isn't real. How many times have I been told my memory loss wasn't due to ECT but to depression? How many times have I been told that, like a lot of other consumers, I must be perceiving this incorrectly? How many times have people told me that my feelings of trauma related to the ECT are misplaced and unusual? It's as if I was raped and people kept telling me not to be upset—that it wasn't that bad. (Oh, wait. That happened too. Separate issue.)

Well, now I'm sitting at my desk and crying—not phlegmy sobs or anything; just prickly tears. I feel like finally, after all these years, my experience is being validated—by the same person, Harold Sackeim, who invalidated it most publicly. (And hey, Miltón, if you're reading this, gimme a call and apologize. That would make this a banner week.)

Through the years Linda Andre, director of the Committee for Truth in Psychiatry, has been an ECT survivor-activist who's galvanized this movement and made me feel whole. She says everything I would say better than I could, so let's just give her the floor. (Side note: But I don't think Sackeim would characterize these results as "permanent." He'd say "long-term.")

ECT Causes Permanent Amnesia and Cognitive Deficits, Prominent Researcher Admits


NEW YORK CITY (12/21/06) -- In a stunning reversal, an article in the journal Neuropsychopharmacology in January 2007 by prominent researcher Harold Sackeim of Columbia University reveals that electroconvulsive therapy (ECT) causes permanent amnesia and permanent deficits in cognitive abilities, which affect individuals’ ability to function.

“[T]his study provides the first evidence in a large, prospective sample that adverse cognitive effects can persist for an extended period, and that they characterize routine treatment with ECT in community settings,” the study notes.

For the past 25 years, ECT patients were told by Sackeim, the nation’s top ECT researcher, that the controversial treatment doesn’t cause permanent amnesia and, in fact, improves memory and increases intelligence. Psychologist Sackeim also taught a generation of ECT practitioners that permanent amnesia from ECT is so rare that it could not be studied. He asserted that most people who said the treatment erased years of memory were mentally ill and thus not credible. The National Institute of Mental Health estimates that more than 3 million people have received ECT over the past generation. “Those patients who reported permanent adverse effects on cognition have now had their experiences validated,” said Linda Andre, head of the Committee for Truth in Psychiatry, a national organization of ECT recipients. Since the mid-1980s, Sackeim worked as a consultant to the ECT device manufacturer Mecta Corp. He never revealed his financial interest in ECT to NIMH, as required by federal law, and, until 2002, did not reveal it to New York officials as required by state law. Neuropsychopharmacology has endured negative publicity over its failure to disclose financial conflicts of journal authors, resulting in the editor’s resignation and a promise to disclose such conflicts in the future; yet there is no disclosure of Sackeim’s long-term relationship with Mecta, nor did Sackeim disclose his financial conflict when his NIMH grant was renewed to 2009 at approximately $500,000 per year. The six-month study followed about 250 patients in New York City hospitals, an unusually large number; most ECT studies are based on 20 to 30 patients. Sackeim’s previously published studies were short term, making it impossible to assess long-term effects. “However, in other contexts over the years – court depositions, communications with mental health officials, and grant protocols – Sackeim has claimed to follow up patients for as long as five years. This raises serious questions as to how long he has actually known of the existence and prevalence of permanent amnesia and why it wasn’t revealed until now,” Andre said. Besides finding that ECT routinely causes substantial and permanent amnesia, the study contradicts Sackeim’s oft-published statements that ECT increases intelligence and that patients who report permanent adverse effects are mentally ill. “The study is a stunning self-repudiation of a 25-year career,” Andre said. The article is available here.

GOP Texan Richard Berns speaks out about "retards"

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I debated for a while whether to post the below comment, but I've decided it's important for readers to know that this kind of sentiment is out there. The person who wrote it, Richard Berns, lists Free Republic as his URL. Free Republic is a conservative message board. The posters there call themselves Freepers, and are fairly extreme in their right-wingedness. You want a live Fox News feed? Rush Limbaugh's pharmacy number? A gun registered to the Second Amendment Sisters? I'm guessing the Freepers will help you out.

I vehemently disagree with their positions, which I like to think are not representative of most Republican points of view. I'm happy to admit there's room on this planet for all species of political opinion, but the Freepers are so extreme, I think they probably embarrass mainstream conservatives. I can't imagine any self-respecting Swift Boater would affiliate with them, and I certainly don't know of any conservative politicians who are linked to them. I don't think they have much credibility.

That's probably a good thing, 'cause here's what Richard Berns wrote:

The mentally ill in this country are an abomination to G-d. Back when America was still Christian and conservative we used to lock the retards up and abuse them and give em lobotomies. Oh for the days we used to use them as fuel in the ovens. GOD BLESS AMERICA! HEIL BUSH!

Sorry for unleashing this on a Funday. I think we have to know what we're up against sometimes.

December 21, 2006

Fair play: Eli Lilly's response

Here is Eli Lilly's official rejoinder (aside from the lawsuit they're readying) to the series the NY Times has been doing about Lilly's marketing of Zyprexa:

Eli Lilly and Company (NYSE: LLY), vigorously objects to the characterization of company practices in a New York Times article based upon selective documents illegally leaked by plaintiffs' lawyers.

"At Lilly, we do not engage in off-label promotion - as alleged in The Times article," said Dr. Steven Paul, Lilly's executive vice president, science and technology. "Lilly is committed to the highest ethical standards and to promoting our medications only for approved uses. We have clear guidelines and extensive training for our sales representatives to help assure that they provide appropriate promotional information that is within the scope of prescribing information approved by the FDA."

Lilly works to bring Zyprexa to physicians who are confronted with the need to diagnose and treat serious schizophrenia and bipolar disorder wherever they practice.

* About half of medical care for serious mental illness takes place in a primary care physician's office. This is due to the fact a large number of people in the United States have no access to a psychiatrist or do not seek psychiatric care.

* Our experience in mental health has taught us that primary care physicians are asking for education on severe mental illnesses, since they see many of these patients in their offices.

* We believe that it is absolutely appropriate to discuss Zyprexa and its indicated uses with primary care physicians in the interest of meeting a critical medical need.

* It is important that the public understand that physicians can and do prescribe medications outside of their approved indications to meet the needs of their individual patients.


"While it is accurate to say that mental illnesses like schizophrenia and bipolar disorder begin early in life -- with a higher prevalence during early adolescence and childhood -- it is simply untrue to assert that these diseases somehow end -- and therefore prescribing for them ends -- in young adulthood," added Paul. "To dismiss the devastating impairment of these disorders throughout a patient's life is wrong.

"Bipolar disorder and schizophrenia are often treated in the offices of primary care physicians. In fact Lilly did research with primary care physicians and found that they were challenged in making the diagnosis of bipolar disorder. Many primary care physicians appreciate the educational outreach Lilly provides in mental illness," he added.

The Times failed to mention that these leaked documents are a tiny fraction of the more than 11 million pages of documents provided by Lilly as part of the litigation process. They do not accurately portray Lilly's conduct. As part of Lilly's commitment to patients and healthcare professionals, many high-level Lilly physicians and researchers -- along with researchers from outside Lilly -- were engaged for a number of years to study the issue of Zyprexa and diabetes. Leaked documents involving these discussions do not represent an accurate view of company strategy or conduct.

Lilly deplores the illegal release of select confidential documents. This illegal and selective disclosure of incomplete information will cause unwarranted concern among patients that may cause them to stop taking their medication without consulting a physician. This is the unfortunate result we saw when plaintiffs' lawyers aggressively advertised about Zyprexa in recent years while searching for clients.

Lilly, a leading innovation-driven corporation, is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations.

Cute fix: Kittens on the bed!

This is Billie Matthews' video of new Oriental Shorthair kittens playing on the big bed for the first time. According to the video description, they were "delighted."

P.S. My cat Augie was an Oriental Shorthair. They're really fun.

Doing the tangi

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The Maoris in New Zealand struggle with rising suicide numbers, and now there's an initiative that would ban traditional funerals in the case of people who take their own lives.

From Stuff.co.nz:

Under the plan, the families of young people who commit suicide would be offered a brief low-key tangi, without the grand speeches, catering, marae stay and extensive iwi visits of a multi-day traditional tangi.

Araiteuru Marae chairman Tom Duff said the move was one of a raft of measures - including hui, youth workshops and mentoring - being considered in response to an upsurge in Maori youth suicides nationwide.

I don't know the meanings of the words "tangi," "marae," "iwi" or "hui," but I suspect banning them will only hurt families trying to work through the grieving process.

Split on suicide tangi ban

More ... on ... Eli ... Lilly

I'm getting out of breath just typing that. Alex Berenson, of the NY Times, is on quite the roll, and I can barely keep up. I read something on a media website yesterday that suggested the Times is presenting all these multipart series as a way to curry awards favor in the last month before the big journalism awards are decided. Whatever the motivation, it's great to see this kind of thing explored in a major newspaper like this. If the mainstream media actually held big pharma to account more often, I bet you'd see big changes.

Disparity Emerges in Lilly Data on Schizophrenia Drug

Offensive? Funny?

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A publicist sent the below email to our music editor, who forwarded it along to me. Usually, when publicists send stuff, it goes out to a huge list of people, so I'm guessing it wasn't just Brian who received it. Which then begs the question: Is this offensive and stigmatizing? Or stupid and harmless? You tell me.

From: redacted

Date: Wed, 20 Dec 2006 16:07:46 -0800

To: 'Brian McManus'

Subject: FW: Christmas Fun!


CHRISTMAS CAROLS

* 1. Schizophrenia --- Do You Hear What I Hear?

* 2. Multiple Personality Disorder --- We Three Kings Disoriented Are

* 3. Dementia --- I Think I'll be Home for Christmas

* 4. Narcissistic --- Hark the Herald Angels Sing About Me

* 5. Manic - Deck the Halls and Walls and House and Lawn and Streets and Stores and Office and Town and Cars and Buses and Trucks and Trees and.....

* 6. Paranoid --- Santa Claus is Coming to Town to Get Me

* 7. Borderline Personality Disorder --- Thoughts of Roasting on an Open Fire

* 8. Personality Disorder --- You Better Watch Out, I'm Gonna Cry, I'm Gonna Pout, Maybe I'll Tell You Why

* 9. Attention Deficit Disorder --- Silent night, Holy oooh look at the Froggy - can I have a chocolate, why is France so far away?

* 10. Obsessive Compulsive Disorder --- Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle,Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells , Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells, Jingle Bells...

[Photo of pretty and obsolete iMac courtesy Apple Inc. Taken by Terry Hefferman.]

December 20, 2006

Also...

If you're interested in the ongoing Zyprexa scandal, head over to Furious Seasons, where once again this Dawdy guy is more serious about things than I know how to be. For one thing, he's not turning himself into an elf.

Protein shake

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When I want to kick back and relax, I start with a hot cup of tea and the most recent issue of the American Chemical Society's Journal of Proteome Research. And because I'm such a faithful reader, I got a sneak peek at the January issue, which is filled with informative articles about, like, alkalines and whatever. Plus, one of my fave researchers, Sabine Bahn, M.D., Ph.D. (pictured here), has led her team to some really cool discoveries about proteins and schizophrenia and red blood cells and stuff like that. The important thing is the brain-tissue vs. body-tissue, but I don't want to confuse everyone. You'll have to read for yourself:

Abnormal proteins linked to schizophrenia found in body tissue

Jewish elf

Click here for holiday cheer.

Because I'm tiny, I really didn't have far to go in the elfamorphisis.

Also in pharma news

Court Orders Lawyer to Return Documents About an Eli Lilly Drug

Well, that was entirely predictable

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I saw this one coming a mile away. Johnson & Johnson's exclusive patent on the antipsychotic Risperdal is set to expire next year, so they did what any big pharma company does in that situation: panic, and then figure out a strategy to milk money out of something that seems like something but is actually nothing.

Invega, a new schizophrenia drug from J&J, is chemically incredibly similar to Risperdal, but different enough to persuade people that they're taking something new. Smart. Also, J&J is trying to cling to their Risperdal patent by saying they're going to study the drug's effect on children, so they need an extension. Hey, J&J! This isn't a term paper! You can't get an extension! (Okay, that's not true. I'm sure they'll it.)

Here's a novel idea: What if a pharma company actually conducted their research and created products and patents based on medical necessity? God only know what would happen.

J&J schizophrenia drug wins federal approval

[This image is the patent drawing for the Wright Bros.' flying machine. I guess Risperdal could get you flying too, if you take enough.]

More of: Cute Psychology Students!

Depression Confession: Angelina Jolie

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I don't know what's going on, but it's suddenly the in thing to talk about your depression. Just as Beyonce's cure was somewhat unconventional, so too was Angelina Jolie's: She imagined herself in a film role she didn't yet have (and still doesn't, apparently).

Side note: In describing her ordeal and subsequent recovery, she uses the word "lass." Why do Americans insist on talking like Brits, all these years after we gained our independence? I read an interview with Ricky Gervais, of The Office, about the U.S. version of the show, which he regards with colonial skepticism: "It’s like a son you didn’t think would amount to anything. You don’t like the way he’s made his money, but at least he’s doing well. You’d rather he’d become a lawyer or doctor, but he owns a casino." Too funny.

Sin City Character Helped Angelina Jolie Get Over Depression

December 19, 2006

En español

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Hola. Como hoy es un dia internacional, es una oportunidad escribir en español, algo que quiero hacer con mas frecuencia. Pero despues de tanto tiempo sin hablarlo, pues, no tengo mucho que escribir. O bien dicho: Ya no puedo escribir como quiero. Es muy triste. Pero soy yo una perfeccionista? Hombre, no. Asi que vamos a intentar—pero sin enfasis. (Lo siento, pero es demasiado dolor recordar cuales palabras los tienen.)

Hoy estoy aprendiendo Photoshop con la ayuda de un libro. El libro esta escrito para idiotas (aunque no es parte del serie "lo que sea para idiotas"). Las lecciones estan claras y bien escritas, pero cada vez que turno la pagina, tengo un ataque de nervios—un panico. No se por que; tal vez es un miedo de fracaso, pero que fracaso? Estoy aqui sola. Nadie sabe lo que hago. Lo peor que puede pasar es que no entiendo algo en el libro y tengo que estudiar mas. Por que el miedo?

He bebido cafe hoy, y para una persona que sufre con ansiedad, cafeina es peligroso. Podria tomar una pastilla bonita de Ativan, pero ... Tomar Ativan para que pudiera estudiar Photoshop? Parece ridiculo, no?

Es interesante que me siento mas libre confesar mis temores cuando escribo en español. Tengo distancia, supongo. Es casi como un susurro, mientras que cuando escribo en ingles es como HABLAR EN MAYUSCULAS!

Vale, como se dice en España. Me voy. Pero les presento esta foto de una chica en Barcelona. La foto no tiene ningun significado, pero me gustan las trenzas.

Speaking of India

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Here's a report of a 24-year-old jawan who killed himself in New Delhi, which according to The Hindu, brings the number of "distress deaths" by armed forces personnel to 130 this year.

But let's not get too gloomy: India is a beautiful and fascinating nation that's always held a special place in my heart. On my List of Things to Do Before I Die, it says, "Go to India" and "Skydive." (Yes, it's a short list.) My favorite images of India—or of anywhere, really—are by photographer Steve McCurry, who I want to be when I grow up. This photo was taken from McCurry's taxi on the way to the airport.

A few weeks back, PW did a food issue, and the theme was sexy food. I wanted to feature Indian cuisine because I like the idea of the sensual heat of Indian cooking, so I asked PW's resident India expert, Susanna Simon, if there were Indian foods that would lend themselves to the theme. She put out the call, and her friend Artee Sehgal answered with the spicy kebabs recipe below. Seems like a nice way to cheer up. Thanks, guys.

Ingredients for the Kebabs: 1lb ground lamb 3 tsps corriander powder 4 tsps cumin powder 1 - 2 tsps RED chilli powder 2 tsps ground ginger 1 tsp ground garlic 1 small finely diced onion handfull of finely chopped corriander

Ingredients for the Veggies:
Salt to taste
Pepper to taste
1 Large Onion chopped lengthwise (Semi Circles)
1 Large tomatoe chopped lenghwise (semi circles)
2 Lemons chopped length wise

The Invigorating Method
Put the lamb in a large mixing bowl and play some nice indian tabla beat.
Add all the ingredients listed above and start kneeding the lamb to the beat of the tabla.
Once you can smell the powerful aroma of the spices mixed in with lamb its time to start making the kebab shapes.
Break pieces of the now kneeded or shall I say needy lamb into medium size balls.
Then roll it around to make a nice ball shape in your palm.
Once you have done this roll it in longer sausage looking shape. (You may also make small meatballs for pastas, or appetizers, or in patty shapes for burgers).
Put some oil in the pan to coat the bottom and put the now sausages in it and let it cook until it done.
You will need to keep turning it so all sides are complete.
Once the sausages are cooked then put them aside on a paper towel so the oil will "slip" or shall I say drain out of it.
With the leftover oil in the pan, sautee the onions, and once they are soft add the tomatoes and lemons.

To Serve:
Put the kebabs and side veggies on a plate and serve with a nice glass of Shiraz

Suicide in China

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I've noticed that when suicide is quantified in both China and India, the reasons for it tend to be pragmatic: bad crops, poverty, family troubles. Now there's more data related to suicide in China, from a study reported by Xinhuanet.com:

•Depression, poor quality of life and unemployment are among the top 10 reasons for suicide in China.
•Serious depression, a previous failed suicide attempt and a strong emotional stimulus are critical warning signs in suicide cases.
•Low living standards, acute interpersonal conflicts and suicide among friends or relatives may also serve as catalysts for people to take their own lives.
•Suicide is often a means for individuals living with mental or incurable diseases to extricate themselves from their situation or relieve their family's burden.
•In the rural areas, young women are more likely to commit suicide on a sudden impulse if some dramatic change or conflict occurs in their families.
•The suicide ratio is three times higher in the rural areas than in the urban areas, and 25 percent more women commit suicide than men.

For more, go here.

[Beijing photo taken by ciro@tokyo via Flickr.]

I like the sound of this

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Here's a refreshing commitment to veterans' mental healthcare that's not seen enough here in the U.S. From PR Newswire:

Veterans Minister Derek Twigg handed over a cheque for £100,000 during a visit to the headquarters of Combat Stress, the Ex-Services Mental Welfare Society, in Leatherhead. The Society specialises in helping those from the Armed Forces and Merchant Navy who are suffering from psychological disability as a result of their service.

Mr Twigg said: "I am committed to meeting the needs of veterans suffering from mental health problems as a result of their service. Each and every one has made an important contribution to UK Defence and for that we owe them an enormous debt of gratitude."

£100k boost for Veterans' mental health

For an excellent look at young veterans' mental health issues after returning from Iraq, read my colleague Cassidy Hartmann's article In Dubious Battle. It's really powerful.

[Photo of Toronto antiwar rally by mjemirzian via Flickr.]

Tuesday's International returns

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Every Tuesday for the past couple months I felt like something was missing. Blame it on the drugs or the ECT, but I completely forgot my schedule!

Monday: Newest news
Tuesday: International
Wednesday: Uh, more stuff
Thursday: Also ... stuff
Friday: Funday!

I guess Wednesday and Thursday could use some perking up. If you have any suggestions on that score, do let me know. But for today, it's all international, so send tips accordingly.

[Lego globe by Eric C. Harshbarger]

December 18, 2006

African mental healthcare in the U.K.

This article is really intense and depressing. It's by an African woman, diagnosed as bipolar, who lives in London and struggles with racism in the system. She points to small things I never would've thought of (because I'm so white), like how in the hospitals they only give patients small-toothed combs. Those combs are suitable for white hair, not black hair. That's why, she says, Africans' hair is so commonly messed up on the psych wards.

"Breaking it down: Mental health and the African community."

What Would Spikol Do? (Bumper sticker in the works.)

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As any regular readers of this messhuggeneh site know, I'm not Christian and therefore find it difficult sometimes to address things that are Christ-related. However, as part of the holiday season, let me address those of you in the audience who do celebrate Jesus' birthday: Holidays can be a stressful time, and you should take care of yourself.

•Make your mental health a priority, along with family and gifts and tree decorating and fruit cakes.
•Don't get caught up in other people's expectations of you.
•Don't drink too much.
•Take your meds.
•Be honest with friends and family when your energy is flagging or you just need a break.
•If you're alone this Christmas, reach out and try to spend a little time in the company of human beings—whether volunteering for a neighborhood shelter or even going to a movie (a cheerful one).
•Try not to indulge in self-defeating fantasies like, "Everyone's happy but me," or "Everyone's got family but me," or "Everyone's having fun but me." (No one's happy; most people don't like the family they have; and nobody's having fun. It's stress and work.)
•Don't overeat but also don't deprive yourself because you're fixated on weight gain.
•Everything in moderation.
•Get enough sleep.
•Don't entirely abandon your routine.

If you're deeply religious, and want a real Christian's perspective on depression, read "Christians: Take Depression Seriously." It talks about the blending of spiritual and physical healing in order to be well. (If it were about Jews, it would say, "Jews: Take Depression a Little Less Seriously.")

[Photo by Liz Spikol]

Art break

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I love graffiti, and there's tons of great wall art here in Philadelphia. I took a bazillion photos of graffiti in Barcelona and haven't been able to make prints yet. But I finally posted them at Flickr, and if you like public art of a grassroots kind, as I do, take a look. It's wild, wacky stuff.

Catalan wall art on Flickr courtesy Spikolina

Depression Confession: Beyonce

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When Destiny's Child broke up, Beyonce was bummed out. She struggled with depression, but It was her mother who pulled her out of it, says Access Hollywood. Mom Tina said: "Why do you think a person wouldn't love you? Don't you know how smart and sweet and beautiful you are?"

If that were a real cure for depression, I would've recovered years ago. My mom says that at least once a day.

Beyonce Speaks About Her Past Depression

[I know Beyonce wears her hair straight these days, but I love it curly, so I'm using an old shot.]

A healthy marketing strategy

Sales reps to help spot farmers in grip of depression

More on the misrepresentation of Zyprexa

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There are further developments about Eli Lilly's marketing of Zyprexa. These kinds of revelations are disturbing. HOWEVER, let's not forget the role doctors play in this. Eli Lilly sent doctors a letter in 2004 with information on the new warnings about Zyprexa and diabetes. It is the responsibility of every prescribing doctor to consider such information before they prescribe. I hold psychiatrists accountable for this mess as well, especially after Lilly settled a multimillion dollar lawsuit on this subject. If prescribing doctors have any integrity at all, they keep up with such developments in their field.

See more reports below:

Drug Files Show Maker Promoted Unapproved Use [New York Times]

Lilly encouraged off-label Zyprexa use: paper [Reuters]

IS LILLY HIDING ZYPREXA FACTS? [Free Market News]

Eli Lilly says New York Times' Zyprexa article short on facts [Forbes.com]

Materials show Lilly pushed Zyprexa use for dementia [NY Times via Houston Chronicle]

December 17, 2006

So scandalous and appalling, I'm posting it on a Sunday

Greetings, fellow citizens of the world. Are you relaxing on a Sunday, perhaps engaging in some home improvement projects? Do you feel bored and wish it were more temperate outside so you could go do fun things? Wait no more! Here's some entertainment for you that'll get you fuming so steam comes out of your ears, a la Popeye. Zyprexa made me gain 30 pounds; thank god I stopped taking it, and had the luxury to do so.

Eli Lilly Said to Play Down Risk of Top Pill

December 15, 2006

More on seclusion and restraints

Following up on a post of a few days ago on this subject, Susan R. writes:

Although I’m the one that sent you the information about the revised Centers for Medicare & Medicaid Services policy on seclusion and restraints, I need to add that, in my opinion, the use of restraints and seclusion should be outlawed. I get a headache when I read the words “appropriate” and “treatment” in the context of the phrase “to assure the appropriateness of the treatment” (to quote the CMS policy).

There are experts who agree with me. Charles G. Curie, until recently the administrator of the federal Substance Abuse and Mental Health Services Administration, made it a goal to eliminate the use of seclusion and restraint in state hospitals when he was Pennsylvania’s top mental health official. As Mr. Curie wrote in Behavioral Healthcare Tomorrow (“Pennsylvania’s Plan to Eliminate Seclusion and Restraint Use,” June 1999), “seclusion and restraint are not treatments; they are treatment failures….Seclusion and restraint are high-risk techniques that may result – and have resulted – in injury or death to the patient, both while the patient is being subdued and afterward. In addition, staff injuries decline in frequency and severity when we eliminate the need for physical interventions with patients. Third, a high percentage of state hospital patients are trauma survivors, and seclusion and restraint are themselves traumatic, for both patients and staff. We cannot cause trauma and effectively care for people. Fourth, use of seclusion and restraint fosters an atmosphere of staff control over patients, rather than the desired treatment partnership.”

Another expert is Joseph A. Rogers, president and CEO of the Mental Health Association of Southeastern Pennsylvania, who has experienced both seclusion and restraints personally. He wrote in the same issue of Behavioral Healthcare Tomorrow (“Restraints: Are ‘Best Practices’ Good Enough?”: “Unless any policy statement outlaws restraints or at least makes it nearly impossible to employ them, there is going to be abuse. If you have an experienced nurse at midnight who is terrified of the patients, policies tend to go right out the window. By the same token, if you don’t have a room equipped with a table to strap people onto, that’s the best guarantee that people won’t be restrained against policy.”

Cute fix: Sleeping duckling

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From Cute Overload.

Tragically: Least surprising headline of the day

Women facing mental-health problems in Darfur

Sad headline of the day

Obese, gay, depressed man needs help

Trouble in Green Bay

A 92-year-old psych patient was dismissed before he was finished with treatment—allegedly because of a desire to cut down the number of beds in the facility overall. Sounds like this guy got caught up in some political infighting, unfortunately for him. At least people are talking about why it was wrong to treat him that way rather than minimizing his problems, as tends to happen with geriatric patients.

Uproar builds over patient's early discharge from mental health center

Still sick

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Oy vey. Now the mucus has moved from my nose into my chest, which is always dangerous for me because of my asthma. I'm tossing back the cold syrup and the Orange-Strawberry-Banana juice Vince bought me and am taking my temperature every five minutes like the neurotic I am. I'm sorry the posts are scarce. I'll marshal my resources and post at least four more times today. How's that?

December 14, 2006

Small new item that's actually big

Lawmakers pass Timothy's Law

Bipolar Made Me Do It: Light a bathroom fire